At degree level, I’d stick to a Chemistry degree which covers all the fundamental aspects in the first year. If it’s a modular degree course, she should be able to make choices in her 2nd and 3rd years to explore her preferred areas. If, not she can specialise post-grad if she really wants to.

Lots of work out there for people with a good Chemistry degree. In the last decade too many people took crap like ‘Forensics’ or ‘Combined Science’ degrees.

Hard Brexit and No Deal are being used interchangeably. They’re not the same thing.

It’s another illustration of how clueless some people are about the whole process.

Paint correction and ceramic coating on a van is likely to cost north of £500 and last anywhere between 6 – 36 months, depending on the product and quality of workmanship.

We* are not prepared for a hard or no-deal Brexit.

*I take ‘we’ to mean everyone and everything within the UK.

Outside rush hour, driving in to Canary Wharf from the M11 is usually a breeze provided there are no accidents.

If I was coming from the West(ish), I’d go round the M25 and come in from the North.

However… What time does your meeting finish? Getting in might be fine but getting back out and round the M25 could be a ballache.

6 years+ with some of the original Bose QC35. The wire is occasionally a bit of a pain, but otherwise they are sublime. They really make planes and trains vastly more comfortable places to be.

My only direct comparison was with some Sennheiser in-ear types which claimed to be noise cancelling (by virtue of acting as ear plugs). They were shit.

By lease I presume you mean personal contract hire (PCH)

I was with Admiral when I had mine a couple of years ago. No issue with not being the owner or registered keeper of the vehicle. I never saw the V5, the car was owned by VW Financial Services. They taxed it every year.

Superdrug – £10pm SIM only = 4gb data with unlimited calls and text. Extra data is pretty reasonable too.

If you want one, pay £2-3k more and get a good one.

Have you ever actually driven a Scooby? You might be disappointed to find your outgoing Golf GTD was a far better car all round…

Does sky news’ stance reflect a change in murdoch’s position?

Sky News’ editorial has been pro-Remain from the outset. It’s basically at the point where your enemies enemy is your friend.

Become an agent and sign him up. It sounds like he’s got the right attitude to be a pro and he’s certainly putting in the practice.

It rhymes with ‘polling’

Weird. **** doesn’t rhyme with that.

It’s clear he holds anyone who doesn’t meet his very narrow view of the world with equal contempt.

RE adaptive cruise control, you’ll need to double check with a Ford dealer. But I don’t think it’s available on the ST.

The issue is, I believe, is a combination of demand for such equipment in that car versus the technical challenge of integrating the radar in to the front end with the larger intercooler etc required by the engine. Not insurmountable, but not deemed worth the effort.

EDIT: Also, get an extended test drive. The Recaro seats in the previous generation were not the comfiest over long distances (lack of lumbar support and overly firm bolster – perfect for keeping you put on fast, twisty roads). But comfort is very subjective.

EDIT EDIT: ST-Line/ST-Line X might be a better bet. ST looks, with more comfort and options (inc. the ACC) and decent poke with the 140ps engine.

How utterly bizarre, and apparently ignorant of the facts, were the results of last nights Commons vote?

So, we ‘must’ now remain part of the EMA? Hooray!

Well, no. EMA means EFTA/EEA, which means four freedoms.

So, when it comes down to it, membership of the EMA will be sacrificed as an unworkable ‘nice to have’.

I still don’t see any realistic alternative to a no-deal Brexit.

Wonder if all those working class chav mothers voted for formula milk shortages.

Wow.

Once the pressure in the system reached a low enough level, the leak will have resealed. The propellant in a/c is a liquid when stored under pressure.

In the absence of any reason to be optimistic about the Brexit process, I’m more than happy to keep moaning about the impact to the Pharmaceutical industry. Today, I’m opining on the risk to patient safety from supply continuity.

According to the EMA, only 58% of companies with centrally licensed products involving the UK in their supply chain are on track to remediate the impact of a hard/no deal Brexit i.e. they’re duplicating UK services within the remaining EEA or pulling out of the UK altogether. The EMA further elaborated that there are 88 human medicinal products which they believe WILL NOT have completed the necessary actions in time.

Some important points to consider here:

1) Only medicines that are of significant therapeutic, scientific or technical innovation are licensed in this way e.g. novel cancer treatments. So we’re not talking about paracetamol.

2) The EMA analysis only considers the impact to the EU i.e. this survey does not asses the impact to the UK market, post-Brexit. This means that as of today, there is a real risk that many more than 88 products may be impacted from a UK perspective.

Now, the UK Department of Heath has also been surveying from a domestic perspective. Their figures are confidential but the high level view is that ‘the majority’ of UK Pharma are planning effectively to deal with Brexit (this is all medicines, not just the novel/advanced stuff). How many is a majority? Well, we know that 52% was enough for A50.

I believe that if there is not mutual recognition between the MHRA and EMA at the end of Brexit, there will be products that fall off the market in the UK and EU. You can’t stock-pile them, they will become unlicensed medicines and Doctors simply will not legally be able to prescribe them. In that case, the likelihood serious adverse events for patients in critical care appear inevitable. For novel and advanced therapies, there simply aren’t alternative products to switch patients to.

I honestly fear that there a real possibility that cost of Brexit could be counted in Human lives. It’s a chilling thought, but as each day passes it comes closer to reality.

It seems this thread and the country in general are obsessed with Tory internal politics. None of that matters now. We are on a direct path to a no deal Brexit.

When this comes to pass, there are facets of the EU who will be so monumentally angry at the U.K. Governmet for allowing it (by their inability to present a credible alternative) they will be poisoned against us for a generation.

Once the country realises what a disaster Brexit has been and starts asking for the damage to be repaired, we will be powerless to do anything about it.

Two groups of people with entrenched, totally opposing views, who loath one another, presided over by a ‘leader’ without a shred of authority?

Do they actually loathe each other?

I believe that these off-site meetings between two groups with disparate interests are much like those I attend in private sector business.

It may be a day of hot air, tantrums and little real progress. But, in the evening everyone meets in the bar and chats, jokes and enjoys some nice food and wine. After all, it’s just work to them and whatever Brexit comes to pass, their work will continue. Of course, as you recognise, this is the real problem. None of the people making the decisions really care about the outcome – they’re too well insulated in either scenario!

Apologies if this was already posted or discussed, but I’ve only just got around to reading it (published 17 May 2018).

It’s the House of Commons Business, Energy and Industrial Strategy Committee report on the Impact of Brexit on the Pharma Industry.

It plainly spells out the negatives for patients of reverting to WTO for trading medicines and that anything other than a frictionless relationship with the EU will be damaging for the UK Pharma industry:

Skip to p.38 if you want the summary.

https://publications.parliament.uk/pa/cm201719/cmselect/cmbeis/985/985.pdf

Same with clinical trials Kelvin, a lot of UK studies in limbo at the moment, because we can’t say what relationship will be re privacy laws etc.

See also UKs cake & eat it position over EMA

Very frustrating for researchers & drug companies

What concerns re privacy laws are there? Any links to articles that spell this out?

You had the right answer with Kumho Ecsta. <£115 a corner fitted on Blackcircles.

I’ve never noticed any sound from ours. Whereas, I could hear the HDD spinning quite clearly in the TiVo box it replaced.

Was Lina a copy? I didn’t think she was. Simply that her DNA had been taken over. Some cool touches:

– The infinity arm tattoo which swapped around. This was referenced when Lina noticed she had a ‘bruise’.

– The view through the water glass in the penultimate scene which showed her hand was mirrored.

I’m assuming the movie was littered with other such subtle references but I’d have to watch it a couple more times to pick up on them all.

https://www.autotrader.co.uk/classified/advert/201802153752520?make=PORSCHE%26model=CAYENNE%26utm_source=Email_a_Friend%26utm_medium=Email%26utm_campaign=Email_a_friend_car

at the moment

Note that with personal contract hire, you are tied in to the term. There is no penalty free way out of it if, for any reason, you no longer want the car. The penalty varies but as an example VW Financial Servicies will charge 55% of the outstanding monthly payments.

EU is also struggling with “chlorine” washed chicken due to salmonella in Poland and the obvious solution being ….

Source for this gem? Unless you can point to something else, the Polish salmonella issue relates to eggs. The root-cause was that Poland stopped using formaldehyde in chicken feed. It has nothing to do with chlorine washing carcasses.

Why Labour’s new customs union proposal is a non-starter

Shanker Signham really is a ****’s ****.

Lazy again, Jamba. Please can you provide a source for Ryanair blaming Brexit?

They blamed low passenger numbers and levels of duty combining to mean they cannot offer low fares to Glasgow. They are, however, increasing services to Edinburgh as well as consolidating other bases from EU cities (such as Berlin) to that same location.

Last time I checked, Edinburgh was still in Scotland and Berlin will remain in the EU post-Brexit. Come on, who is really trolling here Ryanair or you?

Do you have any cash at all? Assuming not:

Current Property = £265k

Current Mortgage = £150k

Current Equity = £115k

———————————–

New Property = £295k

Moving Costs = £10k

New Mortgage = £190k @ LTV of 64%

———————————

Extension = £100k

New Mortage = £290k @ 98%

——————————–

There aren’t many who will lend at 98% LTV. If there are, the rate will be horrendous. Personally, if you can live with the new property as-is, move in, live with it for a couple of years and extend once you’ve paid off some mortgage and the value (hopefully) has gone up so that you can at least borrow under a 90% LTV.

Another thing to consider, does your dream house already exist? If so, does it cost less than £395k?

<span style=”color: #444444; font-size: 16px; -webkit-text-size-adjust: auto; background-color: #eeeeee;”>Councils have plenty of things they can cut spending on, they are simply not prepared to.</span>

please can you list the areas where this council could have cut spending but have refused? Thanks.

If your boy would just like to see a Premier League game, Watford is a good option. Based on my experience, this has become the second team for a lot of Arsenal fans!

<span style=”color: #444444; font-size: 12px;”>”Getting quotes has been nigh on impossible”</span>

Hence why this chap is quoting £2,600 for less than a week’s work.

Here you go:

https://www.arsenal.com/tickets/academy-tickets

I might be wrong, but I think you just rock up for Academy (Now call ‘Premier League 2’) games. It’ll either be free or a couple of quid on the gate.

As all this thread (and I) have recently focused on has been the economic argument for (against) Brexit, this letter to a local paper was a chilling reminder of the utterly nonsensical reasons  some (many, maybe most?) people voted Leave:

(I’ve had to transcribe this)

“I am 70 and so I was born after the war. I do, however, vaguely remember rationing, and I’ve seen the ’50’s through film, and lived as a teenager through the ’60’s. And I know people were happier, and men like my dad whistled while they worked!

Life was simple, and we appreciated more, or am I just looking back through rose-tinted spectacles tat we can’t, for love or money, get anymore?

I voted to leave the EU and would do again. For those who moan, and think only in pounds and pence, I have some advice.

Go and see the film, Darkest Hour, followed by Dunkirk, and when you see how torturous a decision it was for Churchill to fight the likes of Hitler, rather than surrender, and how many young men, and common people were killed, in order to keep this Britain great, and ruled by a sovereign, and not a dictator, and be governed by our own parliament, you should realise Brexit is the only way to thank them for their sacrifices.”

The phrase bespoke is being used to make it sound like we’re getting something special. Something that nobody else would ever get, because we’re so special.

It can be as bespoke as you like, but there are simply no terms under which the UK can leave the EU without damaging the overall economy.

Fortunately, at least in the UK, manufacturers cannot simply raise the price of a medication. So, the short term impact is most likely one of profit but the potential exists for a longer-term price impact for new medicines.

One way it certainly could raise NHS costs is by preventing parallel importation from cheaper EU markets.

Just read the minutes from a December Q&A between various representatives of Pharma industry associations and the European Medicines Agency. The outcome is still that the preparations should be for a Hard Brexit. Therefore, due to the long lead-times involved, Pharma are continuing to commit lots of time and money to preparing for no-deal. It would simply be too late to wait it out with fingers crossed.

Will it ever be possible to count the financial cost of the vote to Leave? In just this one sector, the cost will be counted in hundreds, if not thousands, of millions.

I don’t ride in the mud anymore. When I did (and this was in the dark and distant days of 26″ wheels), a mud specific tyre had a 1.5″ diameter!

People still visit Supermarkets and do their own shopping? How quaint.