I just switched to a new, modern geo, low bb, 29er after years on a 26″. It´s a world of difference, both uphill and down are so much better. I can ride stuff now that I physically couldn´t before…but the pedal strikes are becoming a thing.
I´m using a sram gx eagle setup, and it´s nice, no problems, apart from the 175mm cranks. I´ve ripped the ends to pieces in just a few rides so now I´m looking for 165mm or even 160mm replacements.
If you´re getting a new bike, bear this in mind, and if you can fit them, get shorter cranks.