Had it all my life, hands constantly affected.
E45 or any emmolient drives it mad instantly. I just use white soft parrafin – vaseline. Applied about 10 times a day. Its a hard wearing option. Use Dermovate (the ointment = in WSP not the cream = emollient) when it gets bad.
Anything the takes mositure flares it up = dry weather both crip cold and hot, air conditioning. I come off a plane felling like a pringle.
Plus stress. Reduced massively when I learned to calm my mind a bit.
Lastly, to stop the itching I douse my hands in very hot tap water as needed a few times a day. Not recommended by most doctors but it has worked for 20yrs. This and permanently short fingernails to prevent self harm…