We did the following route on a 4 week trip.
San Francisco
Santa Cruz (Pergolesi coffee shop,surfers,fixies,interesting shops,60's acid burnouts)
Carmel (via Monterey aquarium and 17 mile scenic drive)
(visit Rocky point restaurant for Brekkie on the cliffs 10 miles south of carmel on PCH)
San Louis Obispo (try to visit on weekly farmers market day and pop into madonna inn for a drink)
Santa Barbara wine country (did the Sideways thing)
Santa Barbara
las Vegas
Palm Springs (del marco hotel was great)
Big Bear
San Diego
Big Bear (so nice we went there twice)
La Jolla
Newport beach
Santa Monica