what do you use to immunise someone?

I’ll just leave this here
https://en.wikipedia.org/wiki/Immunization

vaccination is an active form of immunization.

ie there are other forms of immunization

interesting

It’s what my tutor at uni taught me; it applied to live or inactive viral vacccines. No bacterial vaccines, and definitely no protoctista, as we used to call them
That was a parasitology degree.

The bacterial and protoctista preventative measures were antitoxins, innoculations or immunisations. Or just long term prophylatics. So, for instance, the Tentanus Vaccine isn’t a vaccine, as you need a booster every 10 years, or after an injury. You don’t need that with a proper vaccine.

but it’s a niche subject, and niche terminology differentation. So there are more important things to argue about

vaccine against typhoid

EDIT – oh, it’s not worth it

As for bacterial, the HiB vaccine has been spectacular in reducing carriage of a commensal bacteria that leads to meningitis.

But it’s not a vaccine if it works against Bacteria. At least, it wasn’t. Terminology has changed. That’s kinda my point…

Malaria doesn’t have a vaccine. It has drugs, either prophylactic, or palliative.
There is no vaccine that works properly at the moment (there is a drug that even the WHO recommend isn’t taken). And again, it’s against something that isn’t a virus, in that case a Plasmodium, so isn’t a vaccine. In this case, it would be a long term prophylactic.

Like PrEP against HIV isn’t a vaccine; it’s just a drug that stops the virus reproducing. Same with Remdesivir against Ebola and CV19. Kinda like antitoxins

if and when the Covid vaccine becomes available it really is a No Brainer.

If one comes out whilst the disease still has the existing mortality rate, I would definitely be taking one. I have a flu shot every year, and CV is ~10 times as lethal.

or is it ‘pub fact’?

I wish it was, as that would mean I’ve been down the pub!

I’ll see if I can find a more definitive article, but you know, work. These two imply it’s getting better; could be due to all the most susceptible people dying already of course. But also due to weakening

Declining death rate from COVID-19 in hospitals in England

COVID-19: Declining Admissions to Intensive Care Units

Most deadly viruses do it. Here’s HIV for instance https://www.bbc.co.uk/news/health-30254697 or Ebola https://www.ndtv.com/world-news/last-years-ebola-strain-weaker-than-that-of-1976-study-770232

Measures including vaccines don’t have to be 100% effective

Now, I was always taught vaccines are 100% effective when administered properly. Otherwise it’s not a vaccine, it’s palliative care, mitigating the problem. But then I’m the sort of saddo who gets upset when people say vaccine in reference to a bacterial infection.

i’m not entirely sure there will ever be a viable vaccine

the virus is getting, and will continue to get, weaker (viruses don’t really want to kill you; they don’t propagate if they do. They just want to make you pass it on).
So by the time any vaccine is viable, it won’t be needed

Also, vaccines in general aren’t very successful among the elder generations (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739436/ – dated 2009). So any CV vaccine won’t be that successful against the people who need it most

As an example of the last coronavirus to cause a pandemic, read this. https://en.wikipedia.org/wiki/1889%E2%80%931890_flu_pandemic

Give it a couple of years, this virus will just be a normal winter cold, similar to OC43 now. So a vaccine won’t be needed.

course, we’ve got to get to that stage, but any vaccine is not usable yet.

my personal favourite, ever since the classy “They who Dare” extreme sports programme from the mid 90s

manages to be sad, and uplifting at the same time

i think the reason the rivets go in a stainless pan is because they’re aluminium, and dishwashers and aluminium don’t mix

so…going forward, either get stainless rivets, or don’t put them in the dishwasher…

the wife’s gone mad in the last couple of days

* week in devon coming up
* week in norfolk start of august
* most of a week near snowdon middle of august

it’s hard to keep up with the emails asking me what i think of various houses/flats/tents/pubs etc

Xbox store can’t manage more than 30 or 40.

Definitely noticed this the last time the boy downloaded a game. I’d promised him it would be there in an instant (well, not quite but….) and it was downloading at the same speed as the old FTTC cabinet

Virgin are unique by having cable

Oooh no; others are out there. We’re Gigaclear. They do three speeds, 100Mb, 300Mb, and 900Mb

We’re sat at 300Mb. It’s good

Having said that, we were with Vodafone prior at roughly 40Mb, and even with two people working at home, and two kids streaming/playing games there was rarely an issue. More when other people came online – Friday evenings say. But still completely usuable

for inflation purposes, I’ve got one of these

takes it up to about 10-12 bar, when you can then take over and finish it up to 15

makes life a lot easier

Streatley or Goring

Got the river (paddleboard heaven at the moment). Loads of road cycling in the Chilterns and Wessex Downs. Loads of Mountain biking up the ridgeway, and millions of bridleways. Not long slow drags, but very short and sharp. If you’re into long distance running, I think there’s four different centurions a year here.

loads of culture and suff as well, obviously less this year. Pointless at the moment, but got the pub of the year just up the ridgeway

Easy to commute to town; I commuted to bank everyday for 12 years from here. Trains direct in about 45 minutes.

During lockdown it’s been bliss being able to walk out the door, walk for 15km and not see anyone. Busy now, as those in the cities are coming out for the country.

Anaecdotally it’s very busy on the housing market; mates have just put their house on (thursday night), 12 viewings on the saturday, sold on the Monday. Another took slightly longer (two weeks?) but has now gone.

http://www.visitgoringandstreatley.co.uk/

I’ve had a TH5 for about the last 10 years. Pricey, but still going strong.

Started off Mocha, faded quite a lot in the sun, but still superb. Brilliant in the sun, great in the wet. I wear it too much to be honest.

in SQL it would be an ISNULL(field, 0)

So something like this? https://support.microsoft.com/en-gb/office/using-if-to-check-if-a-cell-is-blank-dff4eda1-6187-4b83-b7f6-4c3c0a1e2188?ui=en-us&rs=en-gb&ad=gb
or
https://docs.microsoft.com/en-us/office/troubleshoot/excel/use-formula-evaluate-blank-cell

Glyphosate 360 (I use the Roseate one) is good, and will work eventually

The absolute best thing for Horsetail is Ammonium Sulphamate. It was an actual weedkiller, then the Irish wouldn’t test it on dogs, so it was banned for that purpose in the EU.

You can still buy it as a compost accelerator. Just don’t – whatever you do – mix it up and accidentally spill it on the Horsetail

Ammonium Sulphamate (Sulfamate) – Compost Accelerator, Flame retardant

Chromebook

they don’t go slow. Can do things off line.

My work pc is a HP mobile workstation, with i9, 32gb memory, decent SSD etc
my relatively cheap chromebook knocks it into the park for speed of starting up, and battery life. It’s also a lot lighter (for carrying around). No issue connecting to anything.

What the current ‘sensibly affordable DE’ package du jour?

personally I’d go here, and then [maybe] take a hit on the import tax

https://www.italianbarber.com/pages/custom-shaving-kit-builder

I’ve used the company – and they’re very good.

There’s also the usual Shave Clubs https://www.thepersonalbarber.com/products/discovery-shaving-box – which you can cancel at any time. I’ve not used them however. But, you know, £25 all in. Cheaper than 8 gilette blades

When you need blades, there’s here https://www.razorbladesclub.com/

We have a Dyson Animal upright thing, a few years old, absolutely hate it. Weighs a ton, wife can’t carry it up the stairs. Very thin cheap plastic bits which keep snapping on the bin. The upright lock thing to use the hose works about 1 in 5 times; it normally just falls over with a big crash. Very hard to use on carpets, just seems to get stuck. It does suck stuff up, but a complete PITA to use. Hoping it dies soon so I can buy anything else…

had one for 15 years, and hated it for 15 years. But it kept working. Our cleaner refused to use it (and uses a Henry…). Fortunately the Dyson has just died, so we’ve gone Shark Duo thing

I’m basically centrist. The actual thing I cannot stand in politics is the childish black and white good guys bad guys pantomime.

This

At the moment I feel lost; there is no one to vote for. Can’t vote Tory at the mo, definitely couldn’t vote Corbyn. The Lib Dems were a waste of space.

What we need is a normal Centrist party. The two main parties have been at the extremes (at least from my point of view). Things may be changing

Talking of decent leather saddles (and I know the Cambium isn’t….), but the Spa Cycles titanium clones of Brooks’ saddles are great. And just a bit cheaper.

Thames/Kennet through Reading still seems really high

we were kayaking on the Thames above Pangbourne over the last couple of days, and line of dead vegetation showing the peak flow over winter was about 2ft wide.

The ridgeway is ridiculously dusty. I was overtaken the other night by a motorcross bike, and couldn’t see anything for about 1 minute after he went past.

Still lovely though

Early on, you could download GPXs, then that function went over to the paid version

I’ve just downloaded all my history from Strava, to load the Wahoo data into Garmin. Simple really

https://www.strava.com/athlete/delete_your_account

@doris5000 @ihn

cheers lads. I’m 6ft, with a 38″ chest.I’ll go with my normal medium

@doris5000 (or @IHN of course)

Looking at Rapanui and liking it, but the sizing seems a bit odd.

I’m a medium with Tshirts everywhere….yet at Rapanui, i would appear to be large.

Do they do something others don’t? Or should I just trust my instinct and go for the normal medium?

ta!

It’s not a brewery, and some of them are kinda pricey, but In At Home are very good.

Free delivery over £30

There is also a feature on the Nest that means your Hot Water has to be on above 70c for two hours one a week

As our water only goes for 30 minutes at a time, this was firing in our house. I discovered when it fired it would be in the night at 2am ish. Annoying

when that’s going there’s another icon on the screen https://support.google.com/googlenest/answer/9256656?hl=en

you can turn it off.

And obviously turn off Eco mode. It doesn’t work yet.

Oh also run out of angostura bitters for the cocktails.

Oh the humanity

an all expenses trip around the best vineyards in Tuscany for two, accompanied by a MW. Five days, based in Siena, visiting lovely spots with a meal at each. Last night, spent drinking a wine flight of very expensive wine, talking to the owner, who was heavily into l’eroica.

Got lucky on twitter. Only knew we were going three days before hand

We back onto a large Ash wood; with very steep slopes – 40%?

Anecdotally, our mature ash are fine; the usual dropping of branches in high wind etc (the kids’ trampoline gets covered in branches in winter).
The slightly smaller ones (ie maybe 15cm diameter) do seem to be falling slightly more than normal; maybe 10 this year so far. Now, it’s a steep slope (they’re shallow rooted), and we’ve had a lot of strong northerly winds (the only direction that can get us). So whether it’s a start of things, I dunno. It does mean more wood than I can easily saw though.

The smaller saplings (ie up to 3m in height) are beginning to suffer from dieback quite badly. Give it 20 years and I think the 300 acre wood will be a lot different. Especially with the deer eating the saplings of most other trees…

as an aside….should you want to read the Times, or the Telegraph (I know!), but don’t want to subscribe etc etc

put the link into Wayback Machine – middle right, save page now

It’ll then open all of it, so you can read the page, so this ‘article’

https://web.archive.org/web/20200501080518/https://www.telegraph.co.uk/travel/comment/cycling-lockdown-newgen-bikes/

part of the issue is my boss doesn’t understand what I do. He’s been drafted in from another team, and is more suited over there

I didn’t go for the team leadership role, mostly due to the issue of looking after others; the amount of time you have to devote to others appraisals, and all basically for a slightly inflated job title.

I gave up team leadership/manager-ship almost 20 years ago now. I prefer to be the lowest of the low, yet actually be integral to the running of the firm. Kind of like a blind side flanker in rugby :-)

As my SVP said, if he doesn’t hear anything from me, he knows everything is working well. He knows it’s going badly when I call him…fortunately he is on the same wave length as me.

i have always hated appraisals.

If I want to talk to my boss, or he wants to talk to me, we do so. There’s no need to wait for a formal once a year (quarter) forced meeting. If I want training, I ask. If there’s something wrong, he tells me.

Easier for us as it’s a very small team, where we all work better by ourselves just getting on with it. The manager does have another team, who, shall we say, need a little more hand-holding and day-to-day management

charity money is not allowed to be used for day to day running costs

In that case, good news.

all this NHS charity money is excellent, obviously. But it won’t make a lot of difference

The NHS in England alone gets through £15m an hour (in a normal year). (£134Bn divided by 8760)

Tom Moore is up to £29m

So, it’ll have run out by lunch. It will make a difference, but not a lot.

i have a 5x plus; basically bought for the sapphire glass. I bash watches all the time…

Not used the music, or the Garmin pay, yet. But the maps I use all the time. Obviously replaced the default ones with talkietoaster ones, and during the lock down, whilst walking and running (from home…), I’m exploring. Deliberately getting lost. Exploring new paths.

The maps are invaluable. Seriously.

The other thing on the 5x plus (at least) is the Climbpro. I find it very useful when running up the hills so as I know how long I’m going to be suffering for. It may be on others though

I used DCRainmaker to work out if it were a good buy. There’s a list at the top of the differences

https://www.dcrainmaker.com/2018/06/garmin-fenix5-plus-5s-5x-in-depth-review.html

the Fenix 5 Plus series should likely be called the Fenix 6. It’s got far more features than a mere ‘Plus’ designator deserves, both in terms of hardware updates as well as software ones

Germany … unfettered by an archaic systems of class…etc

They may not be in charge anymore, but they’re still there…with a lot of money

The Kaiser’s Family Wants Its Stuff Back. Germany Isn’t Sure They Deserve It.

Same as in France https://www.bbc.co.uk/news/magazine-37655777
or India https://www.bbc.co.uk/news/magazine-31709924

and is there any difference between an official aristocracy and America? The Kennedys, Clintons, Bushes etc. Those preppies from the North East? https://haenfler.sites.grinnell.edu/prep-preppies/

their own version of aristocracy that valued inheritance, family name, legacy, and “old-money” over all else

Spain still has an hereditary aristocracy; remember Juan Antonio Samaranch? Dodgy Olympic boss? Given a Marquessate. And all the Scandic and Low countries cope with monarchies without a class system so prevalent

The grass isn’t always greener

@molgrips

okay – there may be a certain amount of semantics here
An awful lot of people would have thought the Kaiser was king of Germany in its entirety, rather than just Prussia. Just google “king of germany ww1”

And some of the other monarchs were kings IN Germany, but not kings OF Germany. But a lot were more than

loads of Dukes and associated nobles.

but let’s not derail the thread.