I run my Salsa Vaya like this
1. Hope pro 4 on Wtb Sti25 650b with Soma Cazadero tyres for gravel/off road and tarmac in between.
2. Hope pro 4 on WTB Sti25 700c with Paris Roubaix 32 tyres for the roads
Had toyed with selling the 650b wheels but going to run two sets. With having the same hubs it’s an easy change over.