+1 for Manchester.
I’m originally from the South West (which probably puts up a better fight than Hampshire), but Manchester wins out on variety – the peaks, lakes, Bowland, N. Wales etc.
Though you’d be absolutely screwed without a car IMO (v. frustrating when I first moved up).
Oh, and a quick ‘big up’ (or similarly contemporary call of encouragement and thanks) to the guys at Gisburn. Some lovely lines being built at the moment :D