I’ve got an XL Chameleon which I’ve had for circa 8 years or so. It’s a bit of a Trigger’s broom and in its current incarnation, I’m running it with 160mm Fox 36 Van Rs and a pretty short 80mm stem. Previously I had RockShox Psylo’s (120mm IIRC) on it and a longer 120mm stem.
The ride has changed dramatically, it’s more difficult to climb on, that’s for sure, but it doesn’t preclude me from doing long day rides on it. It’s certainly become more point and shoot when going down a trail.
I’ve not got much experience on frames other than an Orange P7 which is even older, but I really enjoy riding it, more so than the Orange, that’s for sure.