I find it just as easy, if not easier than running tubes. Only had 1 puncture since converting (double spike through the tyre so nothing would have stopped that). Both sets of wheels go up with just a track pump now, saved loads of money on tubes and even more time of faffing about on the trail.
Mine are set up using Duck Tape, so for £2 a roll will set up around 8 rims so the cost is very small even with a bit of jizz every now and again. I can see its not for everyone though, especially if you have the spannering skills of a hippo