Just dont book Holiday Inn at Cramlington/seaton burn its miles out but still called Newcastle – Marriott Gosforth too.
A few independents in Jesmond on Osboune Rd not far from town and an apparently trendy – as im in no way trendy and can never keep up with what is.
Holiday Inn express and Jurys inn off St James Boulevard would be good choices but its in the Gay village (nothing wrong with that of course but prob not your best night out for your situation) just a short walk to the main centre area though.
2 premier inns on Quayside – 1 is quite far east so the best one would be the one under the Tyne Bridge.
Gray St hotel would be good. Thistle opposite Central Station linked above would be a good location for everything near trendy bars but never stayed there – has had loads of work done recently based on scaffolding outside.
PS dont go to Idols or city vault before the game unless your mrs likes pole dancers.