Last year most of the quick teams seemed to do one lap then change rider and sticked with the same strategy through the night. I think that's probably the quickest but switching to riding in pairs through the night means the other two riders get a bit longer off the bike to get some sleep.
Here's a few tips to get you started -
Get there early if you want to camp together or near the arena area as the campsite fills up quickly.
Take plenty of spares, tools and some mud tyres.
Don't ride flat out on the first lap, teams with consistent lap times always seem to do better than those that start fast and run out of steam.
Take some decent lights, a helmet light makes it a lot easier to see where you're going in the more twisty sections.
Make sure there's always someone ready at the handover, you see lots of people riding in to handover only to find their team mate isn't there, if you keep a rough track of lap times you can work out when you need to be ready at the handover and maybe keep a record of who is up next.
There are usually plenty of places to buy food there (burgers, pasta, bacon rolls, etc) but it's worth taking some stuff with you to snack on between laps especially if you want to try and eat healthy stuff.