Loads of options with easy driving in the USA, Canada, Australia, NZ. All ‘big’. Don’t try and do / see too much with only 2 weeks, focus on what looks like a small area to really see it well.
I see Yellowstone-Grand Tetons haven’t been mentioned – start at Salt Lake City which has surprisingly good beer, Jackson, GT, YS, then either Glacier NP, Spokane, Seattle or Sawtooth NF, Portland. I would want 3-4 weeks but we get out of the car and do activities (backcountry hiking, canoeing). In Aus, Tas should take at least 2 weeks to go around, lovely scenery. I love off-the-beaten path Aus but the wildfires will have decimated some areas. Same with the US west and central Rockies, needs a really good look at where exactly to go.
Not mentioned yet, Western Cape in South Africa. ‘Africa-lite’. Good roads with vastly changing landscapes. Loop out and back to Cape Town, or drive from Cape Town to Port Elizabeth (if you want to see elephants) and fly back. The city deserves 3-4 nights then meander (avoid the highways) from the rugged coast through farmland and wineries across mountain passes into arid plains (the R62) then back across the mountain into lush forests and wind-swept beaches (cold water). Rock formations, vast emptiness, star-gazing, penguins, elephants, zebra and other interesting wildlife.