Their use still isn’t commonplace in the uk yet as they are more expensive than warfarin.
As above, nothing to do with cost. Although the drug is more expensive by the time you factor in the cost of the regular blood tests and monitoring of warfarin the switch to rivaroxaban etc. is undoubtably cost effective BUT
There is no proven antidote to rivaroxaban, however, whereas there is with warfarin.
this concentrates the mind. Already had several patients come through needing emergency surgery or suffering bleeding ulcers etc. and other than shoveling in the blood products there is not a lot you can do for 12-24 hours.
As soon as one of the drug companies comes up with an antidote to their new agent expect almost instant switchover and a massive boost to their profits.