Yes, could well be an allergic reaction (the itching and/or swelling round your mouth). Not being funny; are you alone at home or is somebody there ? (anaphylaxis isn’t that likely but possible, given your description of urticaria and perioral swelling)
Doesn’t have to be your penicillin causing it, but it’s common enough
You should talk to your doc, explain the intense itching and oral swelling since taking penicillins (you sure they are all penicillins ?)
Arguably should stop taking in the meantime – depends on what they’re treating and how dangerous it could be to stop treating the eye
(any chance that the symptoms round your mouth are related to the eye problem – ie some spreading of “whatever it is” ?)
There’s pretty much always an alternative to a penicillin
What are you actually taking and what is your eye problem diagnosed as ?
(Bigyinn – rash from amoxicillin with glandular fever is classic; well done ! You’re probably aware it’s not the same as true allergy though)