I looked at this a few months ago.
You can get some really nice light handbuilts. I was looking at Stan’s Alpha rims on a nice light hub like novatech (njee of this board goes on about them 😉 ) They were going to come in <1400g but would cost somewhere around the £400-500 mark. I thought that the open pro rims came in reasonably heavy as do most hubs by shimano (not sure about dura ace though as they might have a titanium freehub and the weight is normally in the steel freehub of lower models).
I looked at the usual suspects of justriding along, strada and wheelsmith.
After looking at hand builts I started to look at factory wheels. Merlin and Planet-x have some really good option.
I contemplated some deeper rims (planet x own offering and the shimano RS80-C50) but decided I mostly race in a bunch and the only time I’m ever going to get off the front is when there is a massive hill to be climbed.
In the end I got some shimano RS80. They came in at 1520g but more importantly I got mine for £280 from planet X so had £120 to spent on something else. Factory seem much cheaper for a given weight, It’s a summer bike for me so things last forever. I’m also light (see the climbing comment) so don’t tend to flex and break things.
I will use my wheels for fast training, long solo rides, racing, sportives. If I was going to commute, use it as my sole all year round bike and use it in harsher conditions I think I would have gone for handbuilts. I’m assuming that when the rims go it will be uneconomical to replace and I will buy new wheels.