I had a small CVI with good recovery about 7 years ago,when I had raised BP (220/160 on admission )otherwise no cardio-vascular problems of note until about a year ago when i had a couple of episodes of chest “tightness” when riding,one of which commenced prior to riding.Saw GP referred to Rapid Access Chest Pain Clinic,seen about 10 days later,I’d been panicking so much about the appointment that when I got there my BP was 140/105 and pulse 104,with normal ECG.Nurse Specialist started me on 1.25 mg of Bisoprolol for BP and Tachycardia and arranged Coronary Angiography, which showed diffuse narrowing of the arteries on the right side,the cardiologist was happy with my medication ( Clopidogrel 75mg ,Candesartan 8mg,Bisoprolol 1.25mg and Rosuvastatin 30mg for long term familial hyperlipidaemia.Fast forward to now,no chest pain since angiography,BP around 120/70 for last 6 months,resting pulse 64,riding around 5 1/2 hours a week ,but due to ? bisoprolol my perceived exertion and heart rate no longer coordinate,which they did very closely before I started bisoprolol.I want to stop the bisoprolol and see how it goes,but saw GP this week,whose attitude was everythings fine,so why change things? I think it’s a very small dose of beta-blocker and if I became symptomatic again,would have no problem restarting it again,would it hurt to try it against medical advice ?