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  • Canine mast cell tumours?
  • Premier Icon oldnpastit
    Full Member

    Anyone with experience of these?

    She was diagnosed a year ago, had surgical removal and chemo (ouch) but it came back within a few months.

    Now she’s on antihistamine, but that obviously isn’t a cure.

    She does seem like she’s a bit more subdued recently.

    Kara, harbinger of death to fox poo

    Premier Icon oldnpastit
    Full Member

    Bump.

    Premier Icon oldnpastit
    Full Member

    The old girl is now limping quite badly, so off to the vet tomorrow 🙁

    Premier Icon myti
    Free Member

    Good luck it’s awful seeing them in pain/unwell. My 12 year old lab has just bounced back after removal of a tumour of the spleen weighing 1.5kgs. So relieved to see her back to normal.

    Premier Icon oldnpastit
    Full Member

    Vet says options are euthanasia, amputation (but might have spread to lymph nodes in which case not going to work) or masivet. Product marketing for masivet looks very impressive but European Medicines Agency is a bit more downbeat.

    Premier Icon andylc
    Free Member

    Masivet is an amazing drug when it works. I have had 6 moths of complete remission (that is tumour disappearing) with it although they always come back eventually. It only works on C-kit positive tumours, these are usually high grade mast cell tumours and the C-kit mutation can be tested for on tissue if you have it. If not then you have the option to trial but it is very expensive. Minimal side-effects though.

    Premier Icon oldnpastit
    Full Member

    Masivet ends up being taken for the rest of her life, at around £3500 per year.

    And apparently after 2 years, only 40% of dogs survive.

    Premier Icon malv173
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    Sounds like a really challenging situation. I think as long as there was a chance that would maintain her quality of life, and it was financially feasible for me, I’d go with that. But not been in that position myself yet. Don’t know how I’ll fare if it happens to one of our two.

    Premier Icon spursn17
    Free Member

    How old is she?

    One of my dogs is 15 now and she has got lumps on her and is getting weak back legs. The vet said at her age to leave the lumps alone and let her enjoy her old age in peace without the stress of treatment, I agreed with the vet as I feel sometimes we keep our pets going for our sakes.
    They have relatively short lives compared to us anyway, so long as they’ve been happy then our job is done, as sad as the end is.

    Premier Icon oldnpastit
    Full Member

    She’s 9 years old.

    If the lumps were not bothering her I would leave them, but the one on her leg is obviously causing her quite a bit of pain. She’s not really walking unless she really has to.

    I’m thinking that amputation might be the best way, assuming the vet agrees it’s doable and the tumors have not spread too far.

    Premier Icon anorak
    Full Member

    Stelfonta (Virbac) is a new treatment for mastcel tumours, in the form of a single injection in the tumour. The tumour dies off and will leave a wound that has to heal on it’s own so indicated only for tumours below hock or elbow. I don’t know anymore about it but maybe worth looking into.
    Such difficult decisions when you love them so much!

    Premier Icon oldnpastit
    Full Member

    Her leg works much better with the dishwasher door open.

    Premier Icon bruk
    Full Member

    Difficult to truly comment without full history and biopsy results etc. Masivet can be very successful but not always. Amputation in a dog of her size usually results in good mobility and quality of life, more so if its a hind limb that is amputated. Advanced imaging can be helpful and in some cases referral to a specialist oncology team can make a big difference too.

    Have a good think about it and always write down all your questions so you don’t forget anything. I love clients with a list in a situation like this. A consultation with an Oncologist can be useful and they won’t pressurise you into going for major surgery or investigation if its not right for your dog or for you either.

    Good luck.

    Premier Icon devash
    Free Member

    One of our previous dogs (6 year old Flat Coated Retriever) went on Masivet and it bought him another 6 months of quality time with us. If money is not an issue then it might be worth checking out.

    Premier Icon oldnpastit
    Full Member

    Vet says amputation would only be to reduce pain in the short term.

    Going to try the masivet, even though it is eye wateringly expensive. They seemed to think that in about 50% cases it provides a cure. If not, I think we’re at the end of the road.

    Premier Icon oldnpastit
    Full Member

    Looks like the Masivet is a bust. We’re going to give it a couple more weeks, but a month in, and it’s not touched it.

    Premier Icon stevego
    Free Member

    Our 4 yo fox terrier got a severe grade mast cell tumor early this year, it was very fast growing. Had to make the horrible decision to have ehr put down a few months ago. We knew it was coming. Once she stopped eating, wouldn’t go for walk and seemed in pain. Forcing more meds down her throat seemed like just punishment for her when it wasn’t treatable. Probably the hardest thing I’ve had to do mentally, holding her while she got the injection but it was the right choice for her.

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