Liteville have been selling bikes like that for years…
From their website….
“Scaled Sizing
The correct frame size of a bike influences the performance capability of an entire bike. Yet it is not only the frame size that is to fit the rider, but also the wheel size. This is why our frames, depending on the frame size and the body height of the rider, can be built with different wheel sizes (24”, 26”, 27.5” and 29”).
Different wheel sizes? Because it makes sense!
Front: rolling smoothly and safely.
When you hit the dirt, your front wheel has the toughest job. That is why it should be as big as possible without having disadvantages regarding the chassis design.
Passing obstacles becomes a lot easier. On top of this, the tracking as well as the braking performance of the front wheel are improved. And there is more to it! The increased gyroscopic force additionally improves the stability of the bike where it is needed most. The rougher the trail is, the more you will have your front wheel support your riding.
Rear: Light, stiff, highly agile
A moderate wheel size in the back makes possible kinematics that allow for a short rear end of the bike. At the same time, passing obstacles with the bigger front wheel is a lot easier, no matter how big the obstacle is. In comparison to a conventional mountain bike with two equally sized wheels, the inertia is reduced and thereby leads to easier acceleration and more control. It goes without saying that a bigger wheel in the back, even for small riders, would allow for better rolling in flat sections, yet in challenging downhill sections, equally sized wheels provide less stability and thus less control. It is not what you expect from a bike that is designed for tough terrain!”