Not sure exactly what part of FF7 it would be, and I’d give different answers on different days, but it’ll definitely be FF7. And not even the obvious ones like Aeris <spoiler> but little beautiful moments all the way through the game- Red XIII’s dad, waking up in the church, zolom kebab, everything with the Turks, heroic missions doomed to fail… Ah it’s so good.
Homeworld probably has the runner up though. Or possibly Stalker:SOC, not for the gameplay but for those moments in the Zone when nothing’s happening at all and you can almost smell it.
I’ve played a lot of Civ… And just occasionally, when it comes together right in the end game, it’s amazing- the music and the beat of the game just click and it’s all coming down to a turn or two and still too close to call… Mostly this sort of game is pretty much done by halfway through and the rest is just tidying up, which is a bummer.