I’m 5’10.5 and reach on my 17 inch seat tube 26er bike is 425mm. ETT 600mm. 32 inch inside leg.
Measuring me for a seat tube comes out as 52cm or 20 inches and I my first bike was that size but a 125mm dropper on a 20 inch had me hoping for Reverb sag on the climbs. The 20 inch bike had an ETT of 600mm too. Nowadays a 20 inch bike would have a much much longer ETT and I’d never fit it!
At least with a 17 inch frame I can slam the drooper to the frame on steep only days. But for climbing my actual correct positioning hasn’t changed much from what I was on the 20 inch bike. I’m just a tiny bit better rider and my head angle is 65 instead of 69!
I could easily manage with an 18 inch frame too depending on the model bike. I just like more room to move about on a bike if possible.