We have built a few frames specifically to take Lefty forks in the past. If all you need is a specific head tube length, since this didn’t alter any of the tube junctions and require changes to the build jig, it wasn’t a hefty upcharge.
Now that the standard headtube is Tapered (and for new orders ZS44/56) this might have become more complicated but drop us a line if you want to look into it properly.
I’m kind of intrigued about Lefty’s myself though my next frame will be a Pinion AC which needs a longer fork than the 130mm they top out at for 2013 (it’ll be getting a 44 RC3Ti – just picked up one of the last sets from Windwave as, unbelievably, Marzocchi have dropped them from the 2-13 range)
If I build up a Helius RC or a 29er hardtail I’ll be looking again.