I run Paselas as the default touring tyre for tandems and singles when on reasonable surfaces. They are half the weight of Marathons and feel very sprightly. I also use Marathons for commuting/rougher conditions (mainly 368’s from Spa) but have a pair of XR’s for real rough road/off road touring.
I did buy a Conti Touring Plus in extremis mid tour. It’s got about 2500 miles on it and apart from being tighter than a (insert inappropriate simile) to get on and off, it’s been fine. I also carry a folding spare on tour and have used it a couple of times.
Summary: good roads/sprightly touring = Paselas, crap roads/ultra reliable = Marathons