Pretty sure it will, but could someone confirm that a Shimano 11 speed cassette (11-42) on a Shimano freehub will work with a Sram rear mech, currently running with Sram cassette (10-42) on an XD driver?

Reason is I need a spare set of wheels able to run with 2 bikes and one of them is 2×10 speed so needs to have a shimano freehub

It will, but may require a quick setup.

Thanks Daffy. Set up not an issue, provided it is compatible