I didn't join this forum to promote colostrum, my brand or the brands that advertise here. I came because one of your members is a customer of mine who took offence at your initial rant and ask me to respond. Not only have you started a rant on a topic you are so plainly not qualified to discuss, you have encouraged a host of other ranters too.
I have gone to considerable lengths to give you all a biology lesson on the function of the gut barrier and its response to heat stress. I have also illustrated biological pathways used by nature to protect you against the influx of luminal toxins into the blood stream.
Foxyrider, I had thought that by giving you your way over my possible lack of clarity in not differentiating the portal circulation functions from the role of the mesenteric lymph system in endotoxemia, you would do as you promised and stop posting your rants on this thread.
Do you want a lesson on the mesenteric immune system and its functions in combating breaches of the gut barrier or would YOU like to begin it and I'll tell YOU if I think YOU're not getting it right. It might be a bit more demanding than a rant, but I'm sure you're up for it. If you don't I am quite willing to try my best. I have conducted enough post-mortem examinations of small intestines to be well aware of the extensive immune system supporting the gut.
Auto immune diseases anyone? How about Ulcerative Colitis. Please see the pilot study below.
Aliment Pharmacol Ther. 2002 Nov;16(11):1917-22.
Use of the 'nutriceutical', bovine colostrum, for the treatment of distal colitis: results from an initial study.
Khan Z, Macdonald C, Wicks AC, Holt MP, Floyd D, Ghosh S, Wright NA, Playford RJ.
Department of Gastroenterology. Leicester General Hospital. Liecester, UK.
BACKGROUND: Bovine colostrum is a rich source of nutrients, antibodies and growth factors.
AIM: To examine the efficacy of colostrum enemas in the treatment of distal colitis using a randomized, double-blind, controlled protocol.
METHODS: Fourteen patients (eight female), with a mean age of 45 years (range, 16-75 years) and mild to moderately severe distal colitis (Powell-Tuck scoring system), received colostrum enema (100 mL of 10% solution) or placebo (albumin solution) b.d. for 4 weeks. Both groups also received mesalazine (1.6 g/day) or, if already taking it, had a dose increment of 1.6 g/day. Disease activity was documented at 0, 2 and 4 weeks.
RESULTS: After 4 weeks, the colostrum group showed a mean reduction in symptom score of - 2.9 (95% confidence interval (CI), - 5.4 to - 0.3), whereas the placebo group showed a mean response of + 0.5 (95% CI, - 2.4 to +3.4). The histological score improved in five of the eight patients in the colostrum group (mean response, - 0.9; 95% CI, - 1.69 to - 0.03), whereas the histological scores only improved in two of the six patients in the placebo group (mean response, 0.2; 95% CI, - 2.4 to +2.6).
CONCLUSIONS: Bovine colostrum enema shows potential as a novel therapy for left-sided colitis with additional benefits over using mesalazine alone. Further studies appear to be warranted.
PMID: 12390100 [PubMed - indexed for MEDLINE
Moderator. These postings must never be deleted from this forum because they reveal the truth. Foxyrider and the others are outed ranters. Puffed-up, self righteous bombasts must always be outed before they turn into Tony Blairs. Let it be a warning to your regular members that the opinions of your resident ranters cannot be trusted.