Radley are somewhat at the lower end of the luxury market in the attractiveness stakes. Mainly becasue they're a bit, er, Cheryl Cole.
Bridge stuff is v nice (Mrs North's daily bag is a Bridge), but has a unique – not very *designer* – style. Quality is super.
Coach make nice stuff, esp since the revival.
Mulberry v nice, though a bit obv in the aspiration stakes. Good quality, though.
LV can be nice, but avoid the godawful LV logo'd stuff. Naff as.
Some of the Smythson bags are nice enough – though you may object to lining the pockets of Sam Cam. I like Smythson stationery, though, and more so it's now made it to the North.
Frankly, though, I don't know an awful lot about ladies bags. For men's bags, there is really only one place.