I have a specialized Alias 143 on my road bike, I run a Selle Italia SLK ladies on my MTB if that helps to compare. I've tried quite a few and its surpirsing how uncomfortable padded saddles are for long rides, although the combination of shorts and saddle is important. It may also pay to check her bike set up, she may not have any weight on her arms in which case its all on her bum, dropping her bars slightly or shortening her stem might also help?
Before I got my riding position sorted I hated the Alias after 1.5 hours or so but since I did a cycle fit I have really liked it. Having said that my first 100 mile ride really broke my a**. Once over that I havent had any problems at all. It seems there is a certain amount of breaking in of both saddle and rider required.
Have you tried getting measured by the LBS? some have that Specialized BG measuring system which makes sure that the saddle is only as wide as your sit bones, any wider and you just end up rubbing on it