My pal and I will be doing the French section from Basel to St Nazaire this June. I think you are doing it in the right direction, the wind should be at your back most of the time. We are going east to west just because of flight logistics. We’re won’t be camping though, we prefer cheap hotels and guest houses.
If it’s anything like the other euro velo river routes it should be quite well sign-posted and have a decent infrastructure. You’ll likely be on tarmac or good gravel, 35mm touring tyres are what you want – comfort over speed. We aim to do 100km per day and that’s really not too hard as long as the weather’s good. Only tips I can give are start early in the day, have a comfy saddle and have the white wine with the fish.
We did the Euro Velo 6 from Budapest to the Black Sea last year. The route is much less organised east of Budapest but it was a good adventure. I just need to add the middle bit and I’ll have cycled across Europe 🙂