Wix.com would be alright but it generates a flash website so not compatible with iPhones, iPads, etc. All depends on what you are selling. For us as we sell iPad accessories this was a no no.
Moonfruit is another flash website builder that is easy to use
My advice would be go with something really easy as you will learn so much and have so many ideas when you design it that you will want to to change it in the future anyway. If your business is successful then before you know it it will be the back end administration of sales that you will be more interested in as this is where loads of time is taken up. We are looking at a redesign so that we can get a e-commerce back end that deals with shipping labels, invoices, notification email, etc