Some of the people originating from D&G:
John Paul Jones became the first US naval hero of the American Revolution, and in many eyes the father of the US Navy. Later in his career he briefly became an Admiral in the Imperial Russian Navy, before ending his life in France. Yet he was born – with the name of John Paul – in 1747, the son of a gardener on the Solway coast south of Dumfries.
http://www.undiscoveredscotland.co.uk/kirkbean/johnpauljones/index.html
David Coulthard
http://www.dcmuseum.co.uk/News/index.htm
Kirkpatrick MacMillan born near Thornhill.
Invented the bike.
John Laurie born in Dumfries
"We're doomed" Dad's Army
J M Barrie was inspired to write Peter Pan by a garden in Dumfies.
William Patterson founder of the Bank of England, was born at Tynwald.
Robert the Bruce was born or died (or maybe did neither)in Lochmaben.