TandemJeremy
I’m not trying to insult your intelligence, I’m only asking you to use it.
Of the published works so far, these are the most relevant and most consistent with user reports.
Br J Nutr. 2010 May;103(10):1425-32. Epub 2009 Dec 24.
Bovine colostrum supplementation attenuates the decrease of salivary lysozyme and enhances the recovery of neutrophil function after prolonged exercise.
Davison G, Diment BC.
Department of Sport and Exercise Science, Aberystwyth University, Carwyn James Building, Penglais Campus, Aberystwyth, Ceredigion SY23 3FD, UK. gdd@aber.ac.uk
Abstract
Oral supplementation with bovine colostrum (COL) has been shown to enhance immunity in human subjects. However, there is limited research on the use of bovine COL supplementation to counter exercise-induced immunodepression, as a model of stress-induced immunodepression, and previous research has focused primarily on salivary IgA. The aim of the present study was to determine the effects of bovine COL supplementation on exercise-induced changes in innate immunity (neutrophil function and salivary lysozyme) in addition to salivary IgA. Twenty healthy, active men cycled for 2 h at approximately 64 % maximal oxygen uptake after 4 weeks of daily bovine COL (n 10) or placebo (PLA, n 10) supplementation. Blood and saliva samples were obtained before and after supplementation, before and after exercise. Exercise induced significant increases in markers of physiological stress and stress to the immune system (circulating neutrophils, neutrophil:lymphocyte ratio, immature granulocytes, atypical lymphocytes and plasma cortisol), but there were no differences between the COL and PLA groups. Significant group x time interactions (two-way mixed model ANOVA) were observed for neutrophil function (stimulated degranulation) and salivary lysozyme concentration and release (P < 0.05). Significant exercise-induced decreases were observed in these parameters, and bovine COL supplementation either speeded the recovery (neutrophil function) or prevented the decrease (salivary lysozyme) in these measures of innate immunity. These results suggest that 4 weeks of bovine COL supplementation limits the immunodepressive effects induced by an acute prolonged physical stressor, such as exercise, which may confer some benefits to host defence.
PMID: 20030905 [PubMed – indexed for MEDLINE]
and this one
Int J Sport Nutr Exerc Metab. 2006 Feb;16(1):47-64.
The effect of bovine colostrum supplementation on salivary IgA in distance runners.
Crooks CV, Wall CR, Cross ML, Rutherfurd-Markwick KJ.
Institute of Food Nutrition and Human Health, Massey University, Auckland, New Zealand.
Abstract
Secretory IgA in saliva (s-IgA) is a potential mucosal immune correlate of upper respiratory tract infection (URTI) status. Nutritional supplements may improve mucosal immunity, and could be beneficial to athletes who are at increased risk of URTI. In this study, 35 distance runners (15 female, 20 male, age 35 to 58 y) consumed a supplement of either bovine colostrum or placebo for 12 wk. Saliva samples were taken prior to training at baseline, monthly during supplementation, and 2 wk post supplementation. Median levels of s-IgA increased by 79% in the colostrum group after 12 wk intervention, and the time-dependent change from baseline value was significant (P = 0.0291). This significance was still apparent after adjusting for training volume and self-reporting of upper respiratory symptoms. This study has demonstrated increased s-IgA levels among a cohort of athletes following colostrum supplementation. While this result is statistically significant, its physiological interpretation must be viewed with caution due to the small numbers in this study and the large variability in s-IgA levels.
PMID: 16676703 [PubMed – indexed for MEDLINE]
I afraid to say that’s all that has been published so far, but a three year program of further resaerch is underway at Aberystwyth.
We can all wish for more complete science on larger sample sizes but these trials were conducted on the product I supply, produced by the world’s largest dairy exporter who can be considered the most reliable source of well processed colostrum meeting the highest quality standards.
If anyone is still unsure of my credentials please cxall 0800 24 25 123