For the road, a rack and Ortlieb panniers.
Used Carradice and Karrimor previously, these are certainly the most waterproof and faff free.
Last well although the cheap bolts rot unless you keep the salt off them and there’s a lot of sticky out bits on the inside, so really pad delicate stuff.
Use a big (8.5) ltr Ortlieb bar bag – great on it’s own for long, changeable day rides and perfect for easily accessible stuff when touring.
You can stick a map on the top too.
Never used front panniers, no issue with them, just never managed to fill two normal size rears and a bar bag.
Camping stuff goes on the rack.
Tools, tubes,etc in a seatpack.