Me & some workmates did a bothy trip a couple of years ago, to Camban bothy. Carrying reasonably heavy backpacks (beer mainly, & yes I know..The Bothy Code blahdy blah)
When we got back to Ratagan Hostel my arse was like a blood orange (I actually thought it must be bleeding)
Straight in the shower & coating of Germolene with local anaesthetic & I was ready for another lap.
Have since used it as a preventative measure with excellent results!