I build wardrobes and office furniture for a living. I use a Kreg pocket hole jig for all my work. It is quick, accurate and strong. All you need to start with is the Kreg R3 kit for about £30 and the correct screws. You must use the right screws but the instruction guide tells you which to use for which material. The only addition I have is the premium face clamp at about £17 which means you can drill your holes fast and accurately.
Most of my work is using 18mm MFC and it’s solid as a rock. I’ve done some using 15mm MFC and MDF and the jig will go down to 12.7 mm. (half inch)
Appleby Woodturnings is where I get all my stuff from. They also supply little plugs to fill in the holes for a neat finish on exposed joints.