I suspect that the bigger jobs boards aren't as effective as smaller more focused ones. Here is a list of sites that came across my desk the other day. A lot of them are specialist boards, but there is usually a variety of roles in each sector.
1Job
Big Hospitality
Brand Republic
Bristol Jobs
Cardiff Jobs
CareerEngineer
Careers & Jobs UK
Careers in Audit
Changeboard
CIMA
eFinancial
eteach
Exec-Appointments
Executives on the web
Fish4Jobs
Food Man Jobs
GAAPweb
Grapevine
Grocer
Guardian Jobs
Gumtree
ICAEW Jobs
Jobs.ac.uk
Jobs4Medical
JobsGoPublic
Jobsmine
Jobsretail
Just Engineers
Key 103
Law Gazette jobs
Law Society Gazette
Legal Week
LondonCareers.net
Milkround
mrweb
Nuclear Careers
Pharmiweb
Planetrecruit
Prospects.ac.uk
Public Jobs Direct
s1jobs
Secsinthecity
Security Cleared Jobs
Telegraph Jobs
TES jobs
Third Sector
Times Online Jobs
Top-Consultant
Totally Legal
VCJobs
Work Moose
Workcircle